This content is not meant to replace a conversation with a healthcare provider. A healthcare provider can evaluate your symptoms and make the appropriate clinical decisions.

In the treatment of hereditary angioedema (HAE)

WHAT IF YOU COULD

WITHOUT DEFLATING EXPECTATIONS?

In the treatment of hereditary angioedema (HAE)

WHAT IF YOU COULD

WITHOUT DEFLATING EXPECTATIONS?

In the treatment of hereditary angioedema (HAE)

WHAT IF YOU COULD

WITHOUT DEFLATING EXPECTATIONS?

Life with HAE can be a burden. Your treatment shouldn’t be.

Not a person
with HAE.

In the treatment of hereditary angioedema (HAE)

WHAT IF YOU COULD

WITHOUT DEFLATING EXPECTATIONS?

Life with HAE can be a burden. Your treatment shouldn’t be.

In the treatment of hereditary angioedema (HAE)

WHAT IF YOU COULD

WITHOUT DEFLATING EXPECTATIONS?

Life with HAE can be a burden. Your treatment shouldn’t be.

In the treatment of hereditary angioedema (HAE)

WHAT IF YOU COULD

WITHOUT DEFLATING EXPECTATIONS?

Life with HAE can be a burden. Your treatment shouldn’t be.

Not a person with HAE.

In the treatment of
hereditary angioedema (HAE)

WHAT IF YOU COULD

WITHOUT DEFLATING EXPECTATIONS?

Life with HAE can be a burden. Your treatment shouldn’t be.

In the treatment of
hereditary angioedema (HAE)

WHAT IF YOU COULD

WITHOUT DEFLATING EXPECTATIONS?

Life with HAE can be a burden. Your treatment shouldn’t be.

In the treatment of
hereditary angioedema (HAE)

WHAT IF YOU COULD

WITHOUT DEFLATING EXPECTATIONS?

Life with HAE can be a burden. Your treatment shouldn’t be.

Not a person
with HAE.

While current HAE treatment options may help, are people with HAE and their doctors making trade-offs among efficacy, tolerability, and convenience?

Understand the trade-offs
Man sitting with knees drawn up and arms wrapped around them, superimposed on a red and white background with a swollen balloon blue foot

Not a person with HAE.

HAE Overview

Learn what HAE is and how it causes attacks.

Two golden heart-shaped balloons against a red background.
Community
& Support

HAE organizations and other resources.

Subscribe to learn more about deflating HAE

Learn more about the trade-offs people with HAE may have to make. Sign up for periodic updates.

Person with HAE

Parent/Caregiver

Patient Organization

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All fields are required.

References

Abdulkarim A, et al. Hereditary angioedema. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. https://www.ncbi.nlm.nih.gov/books/NBK482266/ Allergy & Immunology Medical Center. Glossary of Allergy Terms. https://www.aimedcenter.com/patient-information/patient-education/glossary-of-terms/. Accessed January 19, 2024. Angioedema Centers of Reference and Excellence. Who we are. https://acare-network.com. Accessed January 16, 2024. Anderson J, et al. Allergy Asthma Clin Immunol. 2021;17(1):60. Aygören-Pürsün E, et al. Allergy. 2013;68(8):1034-1039. Aygören-Pürsün E, et al. Orphanet J Rare Dis. 2014;9(99):1-9. Azmy V, et al. Allergy Asthma Proc. 2020;41(Suppl 1):S18-S21. Banerjee A, et al. Cureus. 2023;15(7):e42088. Bernstein JA, et al. Int J Emerg Med. 2017;10(1):15. Betschel SD, et al. J Allergy Clin Immunol Pract. 2023;11(8):2315-2325. Bork K, et al. Allergy Asthma Clin Immunol. 2021;17(1):40. Busse PJ, et al. J Allergy Clin Immunol Pract. 2021;9(1):132-150.e3. Chong-Neto HJ. World Allergy Organ J. 2023;16(3):100758. Christiansen SC, et al. Ann Allergy Asthma Immunol. 2023;131(6):766-774.e8. Covella B, et al. Future Pharmacology. 2024;4(1):41-53. Everyday Health. Speaking hereditary angioedema (HAE): a glossary of terms used to describe symptoms, tests, treatments, and more. https://www.everydayhealth.com/hereditary-angioedema/glossary-of-terms-used-to-describe-symptoms-tests-treatments-and-more/. Accessed January 16, 2024. Farkas H, et al. Clin Transl Allergy. 2021;11(4):e12035. Food and Drug Administration. The voice of the patient - hereditary angioedema. Published May 2018. https://www.fda.gov/files/about%20fda/published/The-Voice-of-the-Patient---Hereditary-Angioedema.pdf. Accessed February 14, 2024. Fouche AS, et al. Ann Allergy Asthma Immunol. 2014;112(4):371-375. Geba D, et al. J Drug Assess. 2021;10(1):51-56. Gülbahar O. Balkan Med J. 2021;38(2):73-81. Hereditary Angioedema International. About HAEi. https://haei.org/about-haei/. Accessed January 16, 2024. Hereditary Angioedema Canada. Learning to live with hereditary angioedema. https://haecanada.org/wp-content/uploads/sites/64/2020/10/HAE-Canada-patient-booklet-Updated-2020-v2.pdf. Accessed January 17, 2024. Hereditary Angioedema International. Frequently asked questions. https://haei.org/hae/faq/. Accessed January 16, 2024. Healthline. What is a hematologist? https://www.healthline.com/health/what-is-a-hematologist. Accessed January 17, 2024. Lo SH, et al. Pharmacoecon Open. 2022;6(2):231-239. Longhurst HJ, et al. Br J Hosp Med (Lond). 2019;80(7):391-398. Lumry WR, et al. Allergy Asthma Proc. 2020;41(Suppl 1):S08-S13. Manning ME. Allergy Asthma Proc. 2020;41(Suppl 1):S22-S25. Maurer M, et al. Allergy. 2022;77(7):1961-1990. Mayo Clinic. Berotralstat (oral route). https://www.mayoclinic.org/drugs-supplements/berotralstat-oral-route/side-effects/drg-20506380?p=1. Accessed January 17, 2024. Mayo Clinic. Hives and angioedema. https://www.mayoclinic.org/diseases-conditions/hives-and-angioedema/symptoms-causes/syc-20354908. Accessed January 17, 2024. National Organization for Rare Disorders. Hereditary angioedema. https://rarediseases.org/rare-diseases/hereditary-angioedema/. Accessed January 3, 2024. Purdue University. College of Science. Career development. https://www.purdue.edu/science/careers/what_can_i_do_with_a_major/Career%20Pages/immunologist.html#:~:text=Immunologists%20are%20research%20scientist. Accessed January 17, 2024. Radojicic C, et al. Allergy Asthma Proc. 2021;42(3):S4-S10. Riedl MA, et al. Ann Allergy Asthma Immunol. 2017;119(1):59-64. Riedl MA, et al. Allergy. 2020;75(11):2879-2887. Riedl MA, et al. Allergy Asthma Proc. 2021;42(3):S17-S25. Santos GM, et al. Cureus. 2023;15(10):e47644. Savarese L, et al. Allergy Asthma Proc. 2021;42(1):e1-e7. Soteres DF, et al. Clin Case Rep. 2021;9(11):e05086. US Hereditary Angioedema Association. https://www.haea.org/. Accessed January 16, 2024. US Hereditary Angioedema Association. Conquering hereditary angioedema together. https://www.haea.org/. Accessed January 16, 2024. US Hereditary Angioedema Association. About hereditary angioedema. https://www.haea.org/pages/p/what_is_hae#:~:text=Symptoms%3A%20HAE%20Attacks,those%20in%20the%20same%20family.%204. Accessed January 16, 2024. US Hereditary Angioedema Association. Treatments. https://www.haea.org/pages/p/treatments. Accessed January 17, 2024. Wedner HJ, et al. J Allergy Clin Immunol Pract. 2021;9(6):2305-2314.e4. Zacek L. Nursing. 2022;52(12):44-50. Zanichelli A, et al. Ann Allergy Asthma Immunol. 2016;117(4):394-398. Zuraw BL. World Allergy Organ J. 2010;3(9 Suppl):S25-8.