This content is not meant to replace a conversation with a healthcare provider. A healthcare provider can evaluate your symptoms and make the appropriate clinical decisions.


A non-profit advocacy organization serving people with HAE and their caregivers. Through a passionate commitment to the HAE community, they offer a wide variety of services and resources that further HAE education, clinical research, community engagement, access to medications, personalized support networks, and a wide range of services to help people living with HAE lead a normal life.

Learn more


A global non-profit network of patient associations dedicated to improving the lives of people with HAE. They are a group of compassionate HAE patients and caregivers who make it their life’s work to raise awareness of HAE, improve time to diagnosis, and fiercely advocate for approval and reimbursement of lifesaving therapies to everyone suffering from HAE.

Learn more


The ACARE program is a joint initiative by GA²LEN (Global Allergy and Asthma Excellence Network) and HAEi (Hereditary Angioedema International) with the aim of developing and accrediting an interactive network of centers of reference and excellence in angioedema management.

Learn more

The third-party resources cited above are for the reader’s information only. Pharvaris does not endorse and is not responsible for the content included in these resources.

Not a person with HAE.

Living with HAE

HAE impacts people’s personal, social, and professional lives.

Not a person with HAE.


Today’s treatment may come with many trade-offs.

Subscribe to learn more about deflating HAE

Learn more about the trade-offs people with HAE may have to make. Sign up for periodic updates.

Person with HAE


Patient Organization


All fields are required.


Abdulkarim A, et al. Hereditary angioedema. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. Allergy & Immunology Medical Center. Glossary of Allergy Terms. Accessed January 19, 2024. Angioedema Centers of Reference and Excellence. Who we are. Accessed January 16, 2024. Anderson J, et al. Allergy Asthma Clin Immunol. 2021;17(1):60. Aygören-Pürsün E, et al. Allergy. 2013;68(8):1034-1039. Aygören-Pürsün E, et al. Orphanet J Rare Dis. 2014;9(99):1-9. Azmy V, et al. Allergy Asthma Proc. 2020;41(Suppl 1):S18-S21. Banerjee A, et al. Cureus. 2023;15(7):e42088. Bernstein JA, et al. Int J Emerg Med. 2017;10(1):15. Betschel SD, et al. J Allergy Clin Immunol Pract. 2023;11(8):2315-2325. Bork K, et al. Allergy Asthma Clin Immunol. 2021;17(1):40. Busse PJ, et al. J Allergy Clin Immunol Pract. 2021;9(1):132-150.e3. Chong-Neto HJ. World Allergy Organ J. 2023;16(3):100758. Christiansen SC, et al. Ann Allergy Asthma Immunol. 2023;131(6):766-774.e8. Covella B, et al. Future Pharmacology. 2024;4(1):41-53. Everyday Health. Speaking hereditary angioedema (HAE): a glossary of terms used to describe symptoms, tests, treatments, and more. Accessed January 16, 2024. Farkas H, et al. Clin Transl Allergy. 2021;11(4):e12035. Food and Drug Administration. The voice of the patient - hereditary angioedema. Published May 2018. Accessed February 14, 2024. Fouche AS, et al. Ann Allergy Asthma Immunol. 2014;112(4):371-375. Geba D, et al. J Drug Assess. 2021;10(1):51-56. Gülbahar O. Balkan Med J. 2021;38(2):73-81. Hereditary Angioedema International. About HAEi. Accessed January 16, 2024. Hereditary Angioedema Canada. Learning to live with hereditary angioedema. Accessed January 17, 2024. Hereditary Angioedema International. Frequently asked questions. Accessed January 16, 2024. Healthline. What is a hematologist? Accessed January 17, 2024. Lo SH, et al. Pharmacoecon Open. 2022;6(2):231-239. Longhurst HJ, et al. Br J Hosp Med (Lond). 2019;80(7):391-398. Lumry WR, et al. Allergy Asthma Proc. 2020;41(Suppl 1):S08-S13. Manning ME. Allergy Asthma Proc. 2020;41(Suppl 1):S22-S25. Maurer M, et al. Allergy. 2022;77(7):1961-1990. Mayo Clinic. Berotralstat (oral route). Accessed January 17, 2024. Mayo Clinic. Hives and angioedema. Accessed January 17, 2024. National Organization for Rare Disorders. Hereditary angioedema. Accessed January 3, 2024. Purdue University. College of Science. Career development. Accessed January 17, 2024. Radojicic C, et al. Allergy Asthma Proc. 2021;42(3):S4-S10. Riedl MA, et al. Ann Allergy Asthma Immunol. 2017;119(1):59-64. Riedl MA, et al. Allergy. 2020;75(11):2879-2887. Riedl MA, et al. Allergy Asthma Proc. 2021;42(3):S17-S25. Santos GM, et al. Cureus. 2023;15(10):e47644. Savarese L, et al. Allergy Asthma Proc. 2021;42(1):e1-e7. Soteres DF, et al. Clin Case Rep. 2021;9(11):e05086. US Hereditary Angioedema Association. Accessed January 16, 2024. US Hereditary Angioedema Association. Conquering hereditary angioedema together. Accessed January 16, 2024. US Hereditary Angioedema Association. About hereditary angioedema.,those%20in%20the%20same%20family.%204. Accessed January 16, 2024. US Hereditary Angioedema Association. Treatments. Accessed January 17, 2024. Wedner HJ, et al. J Allergy Clin Immunol Pract. 2021;9(6):2305-2314.e4. Zacek L. Nursing. 2022;52(12):44-50. Zanichelli A, et al. Ann Allergy Asthma Immunol. 2016;117(4):394-398. Zuraw BL. World Allergy Organ J. 2010;3(9 Suppl):S25-8.