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HAE GLOSSARY

There are many words or phrases that come with an HAE diagnosis. This glossary can help you learn some key terms to help you better understand HAE and its management.

Abdominal attack

An HAE attack that causes swelling in the intestinal wall and can cause stomach pain, nausea, vomiting, and/or diarrhea.

Bradykinin

A natural substance found in the blood. If there is too much bradykinin in a person’s blood, it may result in the swelling experienced during an HAE attack.

C1 inhibitor

A protein in your blood that helps to control swelling in the body. Without enough C1 inhibitor, your body can’t control swelling properly.

Laryngeal attack

This type of HAE attack happens when the major airway in the throat swells up. This type of attack can be life-threatening if not treated as soon as possible.

Subcutaneous attack

A type of HAE attack that affects the skin, typically on the hands, feet, face, or genitals.

Triggers

Something that sets off an HAE attack. Some common triggers are stress, excitement, infections, trauma, a medical procedure, hormone changes, and certain drugs. HAE attacks can also happen without any known triggers.

Warning signs

Before an attack begins, some people with HAE experience warning signs, such as mood changes, anxiety, fatigue, nausea, rash, or a tingling feeling.

Red winged background

Today’s HAE management may be forcing people to choose among efficacy, tolerability, and convenience

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