This content is not meant to replace a conversation with a healthcare provider. A healthcare provider can evaluate your symptoms and make appropriate clinical decisions.
This content is not meant to replace a conversation with a healthcare provider. A healthcare provider can evaluate your symptoms and make appropriate clinical decisions.

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Is HAE management forcing you to make trade-offs?

Living with HAE can be complicated and frustrating.
Knowing how and when to take your medication shouldn’t be.

[An] injection makes you feel like you’re sick, and people see you more sick when you have injections around.

— Andjela, real person living with HAE

TRADE-OFFS WITH HAE INJECTIONS

FEAR OF NEEDLES

Needles may cause anxiety

TRAVEL PLANNING

Injections can be difficult to carry, require more planning, and take up space

FAMILY PLANNING

Treatment options should consider impact on personal choices in family planning

SIDE EFFECTS

May cause pain and/or a reaction at the injection site

REQUIRES TRAINING

Learning to give oneself an injection can take time and require training

TIRED OF NEEDLES

Some people may get tired of giving themselves injections and may avoid treatments as a result

I did try an oral [medication], and the side effects made me feel miserable.

— Gabby, real person living with HAE

TRADE-OFFS WITH HAE ORALS

EFFECTIVENESS

On average, currently available orals may not provide injection-like efficacy™

SIDE EFFECTS

For prevention of attacks, currently available orals may have side effects that could lead people to stop therapy

It’s not an immediate medication. It takes time and for me it takes usually 30 minutes to an hour. And so in that time, I could still have progression of my disease, and so it’s a waiting game as well.

— Emma, real person living with HAE

TRADE-OFFS WITH HAE INFUSIONS

TIME CONSUMING

May require travel to an infusion center

HARD TO SELF-ADMINISTER

May be hard to find a vein or get IV to work

CONFLICTS WITH PLANS

May interfere with personal and work plans

SIDE EFFECTS

May cause headaches, nausea, rash, and fever

NEED ASSISTANCE

May need other people for help giving IV

TRAVEL ISSUES

When away from home, hard to give oneself an IV

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People with HAE may not be living their life to the fullest if trade-offs get in the way

Click a balloon or the buttons below to better understand decisions people with HAE have to make.

Real person living with HAE.

Default HCP Image Convenience HCP Image Efficacy HCP Image Tolerability HCP Image
Effectiveness
Side effects
Convenience
Injections
Orals
Infusions
Injections
Orals
Infusions

While current HAE management may help, are you making trade-offs among effectiveness, side effects, and convenience?

While effectiveness is important in HAE management, people also prioritize few side effects and convenience

People want few side effects AND an effective management that fits into their lives

Convenience is important, but people with HAE also value effectiveness and/or few side effects

How can something so effective also be so hard for some people to take and carry around?

What good is a treatment that fits your life if you may not be able to trust it?

Should you have to schedule your whole life around your HAE?

Until people with HAE can get efficacy, minimal side effects, and convenience, they may be hidden in compromise.

GET THE FACTS

There are two ways to manage HAE

  • Prevent attacks
  • Treat attacks if they occur

Attacks may be triggered by injury, stress, or even excitement—but may also appear for unknown reasons

Because HAE is rare and healthcare providers may not easily recognize it, attacks are often mistaken and mistreated as allergic reactions or appendicitis

The usual treatments healthcare providers give for allergies will not work for HAE

  • Allergy medicines, corticosteroids, and epinephrine (adrenaline) do not work for HAE attacks
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Important Role of Bradykinin

Discover how it causes swelling
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Living with HAE

See how HAE burdens lives

References

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